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CVE-2026-48977 is an arbitrary memory write vulnerability in the OpenSlide library affecting versions 3.4.1 and 4.0.0. It allows an attacker to write arbitrary values to attacker-controlled relative memory offsets by supplying a crafted Ventana BIF slide file, potentially resulting in a crash or arbitrary code execution. The vulnerability was published on June 8, 2026, and is fixed in OpenSlide 4.0.1. It carries a CVSS v4.0 score of 7.7 (High), reflecting a worst-case scenario of remote code execution in a network service processing user-provided slide files (GitHub Advisory).
The root cause is improper validation of quantity fields in input (CWE-1284), which enables use of an out-of-range pointer offset (CWE-823), ultimately resulting in a write-what-where condition (CWE-123). When OpenSlide parses a maliciously crafted Ventana BIF file, it fails to properly validate size or length values, allowing an attacker to control the offset of a memory write operation. All supported platforms and configurations running the affected versions are vulnerable. The vulnerability was reported by researcher Erik Lening (credited as 'hollowpointer') and is referenced by commit 2be88bd in the OpenSlide repository (GitHub Advisory).
Successful exploitation can result in a crash (denial of service) or, in the worst case, arbitrary code execution on the system running the vulnerable OpenSlide library. In network-facing services that process user-supplied slide files — such as digital pathology platforms or web-based slide viewers — a remote attacker with the ability to upload files could achieve full compromise of the service's confidentiality, integrity, and availability. The impact is scoped to the vulnerable system itself, with no direct subsequent system impact identified (GitHub Advisory).
The CVE status was listed as 'Reserved' at the time of initial Feedly ingestion (June 8, 2026), with the full advisory published shortly after. The attack vector is Network with High Attack Complexity, requiring Low Privileges and no User Interaction. Nessus detection plugins (IDs 319667, 321437, 321462) have been published, indicating scanner-level detection capability (Tenable). No public proof-of-concept exploit code, in-the-wild exploitation, or threat actor attribution has been reported. EPSS score and CISA KEV catalog status are not currently available for this CVE.
.bif files submitted to slide processing directories; files with unusual or oversized metadata fields in Ventana BIF format.The vulnerability is fixed in OpenSlide 4.0.1; all users running versions 3.4.1 or 4.0.0 should upgrade immediately. No configuration-based workaround is available, as all configurations on all supported platforms are affected. As an interim measure, operators of network services should restrict file upload capabilities to trusted users and validate file types server-side to reduce exposure until patching is complete (GitHub Advisory). Fedora and other Linux distributions have begun issuing updated packages (Linux Compatible).
The vulnerability was covered by the German Linux security news site Pro-Linux, which noted the arbitrary command execution risk in OpenSlide (Pro-Linux). Fedora issued package updates addressing this and other vulnerabilities. No significant broader media coverage or notable researcher commentary beyond the official advisory has been identified at this time.
Fix availability across major Linux distributions and their releases.
bookworm
openslide: 3.4.1+dfsg-6+deb12u1
sid
openslide: 3.4.1+dfsg-9
trixie
openslide: 3.4.1+dfsg-7+deb13u1
Source: This report was generated using AI
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